// PROOF OF USEFUL WORK · SOLANA BLOCKCHAIN

LIFE COMPUTE

DECENTRALIZED CANCER DRUG DISCOVERY NETWORK · POWERED BY BOLTZ2 MOLECULAR DOCKING

Your GPU was wasting electricity.
Now it's fighting cancer.

TP53 · MOST MUTATED GENE IN CANCER · KRAS · UNDRUGGABLE FOR DECADES · BRCA1 · HEREDITARY CANCER SUPPRESSOR · MYC · ACTIVATED IN 70% OF HUMAN CANCERS · ABL1 · TARGET OF GLEEVEC · IDH1 · 80% OF BRAIN GLIOMAS · FLT3 · 30% OF LEUKEMIA CASES · BCL2 · APOPTOSIS REGULATOR · EGFR · LUNG CANCER DRIVER · PARP1 · DNA REPAIR TARGET · TP53 · MOST MUTATED GENE IN CANCER · KRAS · UNDRUGGABLE FOR DECADES · BRCA1 · HEREDITARY CANCER SUPPRESSOR · MYC · ACTIVATED IN 70% OF HUMAN CANCERS ·

// mission_statement.md

OUR MISSION

LIFE Compute exists for one reason — to accelerate the discovery of cures for cancer and other diseases by mobilizing the world's idle GPU compute power.

We believe that the computational resources needed to find life-saving drugs should not be locked behind the walls of pharmaceutical companies or limited by research budgets. Every gaming PC, every mining rig, every idle GPU is a potential instrument of healing.

Through blockchain-verified proof-of-useful-work, we align economic incentives with meaningful science. Miners earn $LIFE tokens. Patients get better drugs. Humanity wins.

When a miner discovers a novel molecule that scores in the top 10% for its target and is confirmed by an independent validator, that discovery is permanently minted as an NFT on the Solana blockchain — a certificate of scientific achievement owned by the LIFE Compute Foundation and available for licensing to researchers and pharmaceutical companies seeking to develop the next generation of cancer treatments. Your GPU finds the cure. The blockchain remembers it forever.

ZERO PRE-MINE. ZERO TEAM ALLOCATION.
Every $LIFE token ever created represents real scientific work — real molecules screened against real cancer targets by real people who chose to make their compute count.

∞No Supply Cap — Earned Only
2,000Cancer Targets
6.5 minEpoch Duration
0Pre-mine / Team Alloc
<30WAvg Power Draw

// The Problem

10 million people die from cancer
every year.

The SAVI-2020 library contains 1.75 billion synthesizable molecules. Screening even a fraction against a single protein target requires resources available only to the largest pharmaceutical companies. Most promising candidates are never tested.

Meanwhile, billions of dollars of GPU compute burns electricity solving mathematical puzzles that help no one.

01
Mine

Your GPU runs Boltz2 — the same molecular docking AI used by MIT and Recursion Pharmaceuticals — screening drug candidates against validated cancer targets.

02
Validate

Independent validator nodes re-score every submission using real Boltz2 GPU inference. No fake scores get through. 2-of-N consensus required.

03
Earn

$LIFE tokens are minted directly to your Solana wallet. Every token represents a genuine contribution to cancer research. Zero pre-mine. Zero team allocation.

04
Discover

All results stored permanently on Solana blockchain. Open to researchers worldwide. LIFE Compute asserts no IP over discovered molecules — findings belong to humanity.


// Cancer Target Portfolio

2,000 validated
cancer proteins.

Curated from the most clinically significant proteins in oncology. Every target has MSA files for accurate Boltz2 structural prediction.

HARD · 0.9 $LIFE
TP53

Mutated in 50% of all cancers

HARD · 0.9 $LIFE
KRAS

85% of pancreatic cancers

HARD · 0.9 $LIFE
BRCA1

Hereditary breast/ovarian cancer

HARD · 0.9 $LIFE
MYC

Activated in 70% of human cancers

HARD · 0.9 $LIFE
IDH1

80% of low-grade brain gliomas

HARD · 0.9 $LIFE
FLT3

30% of AML leukemia cases

MED · 0.7 $LIFE
EGFR

15% of lung adenocarcinoma

MED · 0.7 $LIFE
BCL2

Venetoclax target — lymphoma

MED · 0.7 $LIFE
PARP1

DNA repair — Olaparib target

MED · 0.7 $LIFE
ABL1

Gleevec (Imatinib) target — CML

EASY · 0.3 $LIFE
CDK4

Palbociclib target — cell cycle

EASY · 0.3 $LIFE
VEGFR

Tumor angiogenesis — Sorafenib


// Tokenomics

The only token you earn
by doing real science.

$LIFE cannot be pre-mined or allocated. The only way new $LIFE is ever created is by contributing genuine GPU compute to cancer drug discovery.

There is no ceiling on $LIFE. There is only the work. Every token in existence is proof that a real computation happened — a real GPU, a real target, a real independently-verified result. Supply does not stop at a number. It stops when there is nothing left to discover.

Total supply is a live figure, not a target. At every moment it is defined as total minted minus total burned. It rises only when real work is verified and mints new $LIFE through the program’s official reward-payout path. There is no fixed cap and no halving schedule.

$LIFE can only ever be created by real, verified work — running inference against real cancer targets, independently confirmed by a second machine. There is no other way for new $LIFE to come into existence. Once earned, it can be freely held or traded — but no one can ever buy their way into being the one who discovered it.

$LIFE is a standard SPL token: no transfer hook, no burn-on-transfer, no restriction on trading once earned. A miner who earned it may sell or trade it on any Solana DEX. The market redistributes already-earned tokens — it never creates new supply.

Total Supply
LIVE

Minted minus burned. No cap, no ceiling.

Pre-mine
ZERO

Not one token before launch.

Team Allocation
ZERO

Founders mine like everyone else.

Blockchain
SOLANA

Fast finality. Sub-cent fees.

Halving Schedule
NONE

Flat rewards. No time-based reduction.

Emission Ends
NEVER

It stops when there is nothing left to discover.

TierExample TargetsReward (flat)Notes
HardTP53, KRAS, BRCA1, MYC, IDH10.9 $LIFENovel / poorly characterized
mRNA SilencingMYC_mRNA, KRAS_mRNA, BCL2_mRNA0.9 $LIFEmRNA silencing targets (IDs 2000–2029)
CRISPR gRNATP53_CRISPR, KRAS_CRISPR, EGFR_CRISPR0.252 $LIFEgRNA knockout targets (IDs 3000–3009)
MediumEGFR, HER2, BCL2, PARP1, ABL10.7 $LIFEPartial structural data
EasyCDK4, VEGFR, NTRK10.3 $LIFEWell-characterized pocket
Discovery BonusTop score for any target weekly100 $LIFEBest in network

Rewards are flat — they do not decrease over time or with cumulative supply. The one reduction that applies is a per-target maturity taper (100+ confirmed hits → 75%, 1,000+ → 50%), reflecting diminishing scientific return rather than token scarcity. Minimum reward: 1 raw unit.

This does not mean $LIFE cures disease. It means $LIFE only exists where real computational science — narrowing the search for what might — has genuinely happened.

// For Research Labs

Get paid to screen,
before you spend to test.

Every lab knows the real cost of discovery — reagents, equipment time, staff hours — spent testing candidates that mostly won’t work. That’s simply how the process goes; most fail.

LIFE Compute is a network of computers running real, independently-verified computational drug screening — protein docking, mRNA targeting, CRISPR guide RNA design — against real cancer targets. Every result gets checked twice, by two separate machines, before it’s accepted as genuine.

Your lab can point spare computer time at this screening instead of letting it sit idle. Every real, verified discovery earns $LIFE — a digital token you receive automatically for genuine, confirmed results, the same way you’d be compensated for any real contribution.

No crypto experience needed to participate. The system runs on Solana, a fast, low-cost public ledger, purely as the record-keeping layer that verifies and tracks results — you don’t need to understand blockchain to benefit from it, only to run the software.

Once you’re running the miner, LIFE Agent — an AI assistant built into your local dashboard — can answer questions about how the network works, how to get started, and what’s happening with your own submissions. It activates once you add your own Anthropic API key to the dashboard’s configuration.

01
Screen First

Narrow the field computationally against validated cancer targets — before a single reagent is consumed.

02
Verified Twice

Two independent machines re-score every result. Nothing is accepted as genuine on one machine’s word.

03
Earn While You Screen

Confirmed results earn $LIFE automatically. Idle compute becomes a funded contribution.

04
Bench Only the Best

Bring only your strongest, already-validated candidates to the wet lab.

The result: instead of spending your budget to find out which candidates might work, you narrow the field computationally first — earning along the way — and only bring your strongest, already-validated candidates to the bench.

// Get Started

3 steps.
Under 5 minutes.

If you can play modern games, you can mine $LIFE. Minimum: NVIDIA GPU with 8GB+ VRAM, 16GB RAM, Ubuntu 20.04+ or Windows 10/11.

1
Download

Choose your platform:

↓ Windows .exe ↓ Windows .msi ↓ Linux AppImage ↓ Linux .deb ↓ macOS .dmg ↓ HiveOS .tar.gz

Or install via CLI:

curl -sSL https://raw.githubusercontent.com/life-compute/miner/main/install.sh | bash
2
Connect Your Solana Wallet
~/.life-compute/bin/life-compute wallet connect
3
Start Mining
docker run -d --gpus all --name life-compute-miner -v ~/.life-compute:/root/.life-compute ghcr.io/life-compute/miner:latest


HiveOS miners: flight sheet URL → https://github.com/life-compute/miner/releases/download/v2.0.0/life-compute-hiveos.tar.gz


// CRISPR gRNA Optimizer

CRISPR Guide RNA
Optimization

Drugging the undruggable.

LIFE Compute is the first decentralized network to optimize CRISPR guide RNA sequences for cancer gene editing alongside small molecule and mRNA drug discovery.

CRISPR-Cas9 won the 2020 Nobel Prize in Chemistry. It works by using a 20-nucleotide guide RNA to find and permanently disable cancer-driving genes. Finding the optimal guide RNA for each cancer target is one of the most computationally intensive challenges in modern oncology.

LIFE Compute miners now solve it — running three-score evaluation on every gRNA candidate:

🎯
On-Target Efficiency

Alignment to the mutation-site consensus window with PAM proximity scoring. High score = gRNA anchored precisely at the cancer hotspot.

🛡️
Off-Target Risk

Seed sequence screened against curated repetitive-element blacklist (Alu, LINE-1, SINE-R, telomeric). Prevents dangerous off-target cuts in healthy tissue.

💉
Delivery Compatibility

GC-content window and thermodynamic stem-loop scoring for lipid nanoparticle and AAV delivery. Ensures the guide survives the delivery vector.

// 10 CRISPR Cancer Targets Active

TP53 KRAS BCL2 MYC EGFR HER2 BRCA1 PDL1 TERT CDK4
CRISPR TIER
All 10 CRISPR targets
0.252 $LIFE
per confirmed novel gRNA discovery

Top-scoring novel gRNA sequences are minted as Discovery NFTs — permanent on-chain proof of first computational discovery, available for licensing to CRISPR therapeutic developers.

// Discovery NFTs

Every great discovery
remembered forever.

When a miner discovers a novel molecule that ranks in the top 10% of all confirmed hits for a cancer target, LIFE Compute mints a permanent NFT on Solana — an immutable record of that scientific moment.

🔬
STEP 01
Discover

Your miner screens novel ZINC15 molecules and mutants against validated cancer targets using Boltz2 GPU scoring.

⛏️
STEP 02
Mint

Top-10% hits that are validator-confirmed on-chain automatically trigger a Metaplex NFT mint on Solana — no action needed.

💎
STEP 03
Sell

Discovery NFTs are held by the LIFE Compute Foundation and made available to pharma, biotech, and collectors who value provable scientific firsts.

🧬
STEP 04
Impact

100% of sale proceeds go to the LIFE Foundation to fund further cancer drug discovery research and network expansion.

🚫 REF
NOVEL MOLECULES ONLY
TOP 10%
SCORE THRESHOLD
ON-CHAIN
VALIDATED ON-CHAIN
100%
TO FOUNDATION

“The discovery of KRAS inhibitors after thirty years of failure is proof that every impossible target eventually falls. The question is only who finds the key first.”

— ONCOLOGY RESEARCH, 2021 · KRAS G12C BREAKTHROUGH


Meet the Creator

Joshua Adams — Founder, LIFE Compute

Joshua Adams

Founder, LIFE Compute

"Building decentralized infrastructure for cancer drug discovery — one GPU, one epoch, one confirmed hit at a time."

@AdamsJosh69520